2025
Iversen, Rasmussen, Folkvardsen et al. Four novel nontuberculous mycobacteria species: Mycobacterium wendilense sp. nov., Mycobacterium burgundiense sp. nov., Mycobacterium kokjensenii sp. nov. and Mycobacterium holstebronense sp. nov. revived from a historical Danish strain collection. IJSEM.
2024
Hall J, Mekapothula S, Coxhill R, et al. Surface-functionalised copper oxide nanoparticles: a pathway to multidrug-resistant pathogen control in medical devices. Nanomaterials (Basel).
Bhandari S, Kuehne S, Camilleri J. Assessment of a light-curable hydrogel to be used for root canal obturation. J Dent Res.
Hollingshead S, McVicker G, Nielsen MR, et al. Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system. mBio.
Shah SN, Knausenberger TB, Pontifex MG, et al. Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor. Gut Microbes.
Snobre J, Meehan CJ, Mulders W, et al. Frameshift mutations in the mmpR5 gene can have a bedaquiline-susceptible phenotype by retaining a protein structure and function similar to wild-type Mycobacterium tuberculosis. Antimicrob Agents Chemother.
Graf FE, Goodman RN, Gallichan S, et al. Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales. Nat Commun.
Read DS, Gweon HS, Bowes MJ, et al. Dissemination and persistence of antimicrobial resistance (AMR) along the wastewater-river continuum. Water Res.
Muchova M, Kuehne SA, Grant MM, et al. Fusobacterium nucleatum elicits subspecies-specific responses in human neutrophils. Front Cell Infect Microbiol.
Das, S.K., Negus, D. How do Gram-negative bacteria escape predation by Bdellovibrio bacteriovorus? npj Antimicrob Resist.
Chen JH, Raman V, Kuehne SA, Camilleri J, Hirschfeld J. Chemical, antibacterial, and cytotoxic properties of four different endodontic sealer leachates over time. J Endod.
Afolayan JS, Varney AM, Thomas JC, McLean S, Perry CC. A rapid microwave approach for 'one-pot' synthesis of antibiotic conjugated silver nanoparticles with antimicrobial activity against multi-drug resistant bacterial pathogens. Colloids Surf B Biointerfaces.
Shutt-McCabe J, Shaik K, Hoyles L, McVicker G. The plasmid-borne hipBA operon of Klebsiella michiganensis encodes a potent plasmid stabilization system. J Appl Microbiol.
Floras F, Mawere C, Singh M, et al. The putative virulence plasmid pYR4 of the fish pathogen Yersinia ruckeri Is conjugative and stabilized by a HigBA toxin–antitoxin system. Biology.
Varney AM, Smitten KL, Southam HM, et al. In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions. ACS Infect Dis.
Aly YM, Zhang Z, Ali N, et al. Ceramic conversion treated titanium implant abutments with gold for enhanced antimicrobial activity. Dent Mater.
McLean S. What is antimicrobial resistance and why is it a problem? In: Masey O'Neill H, Burton E, Scholey D Pre and Probiotics for Poultry Gut Health. CABI.
Muguruza AR, Odyniec ML, Manhota M, et al. Antibiotic entrapment in antibacterial micelles as a novel strategy for the delivery of challenging antibiotics from silica nanoparticles. Microporous and Mesoporous Materials.
Behruznia M, Marin M, Farhat M, Thomas JC, Domingo-Sananes MR, Meehan CJ. The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference. eLife.
Machado E, Vasconcellos S, Gomes L, et al. Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species. Microb Genom.
James B, Reesaul H, Kashif S, et al. The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli. NPJ Antimicrob Resist.
Varney AM, Mannix-Fisher E, Thomas JC, McLean S. Evaluation of phenotypic and genotypic methods for the identification and characterization of bacterial isolates recovered from catheter-associated urinary tract infections. J Appl Microbiol.
Tzfadia O, Gijsbers A, Vujkovic A, et al. Single nucleotide variation catalog from clinical isolates mapped on tertiary and quaternary structures of ESX-1-related proteins reveals critical regions as putative Mtb therapeutic targets. Microbiol Spectr.
Mekapothula S, Chrysanthou E, Hall J, Nekkalapudi PD, McLean S, Cave GWV. Antipathogenic applications of copper nanoparticles in air filtration systems. Materials (Basel).
Dahlquist-Axe G, Standeven FJ, Speller CF, Tedder A, Meehan CJ. Inferring diet, disease and antibiotic resistance from ancient human oral microbiomes. Microb Genom.
Bhandari SS, Palin W, Kuehne SA, Camilleri J. Investigating best practice for specimen preparation for biological testing of root canal sealers. Dent Mater.
Duodu R, Linke D, Leo JC. Fluorescent labeling of outer membrane proteins using the SpyCatcher-SpyTag system. Methods Mol Biol.
Meuskens I, Leo JC, Linke D. Recombinant expression and overproduction of transmembrane β-barrel proteins. Methods Mol Biol.
Aruhomukama D, Galiwango R, Meehan CJ, Asiimwe B. Enhancing genomics and bioinformatics access in Africa: an imperative leap. Lancet Microbe.
Domingo-Sananes MR, Meehan CJ. The population genetics of prokaryotic pangenomes. Nat Ecol Evol.
Beavan A, Domingo-Sananes MR, McInerney JO. Contingency, repeatability, and predictability in the evolution of a prokaryotic pangenome. Proc Natl Acad Sci U S A.
Hoyles L. Gut microbiome and hepatic steatosis (steatotic liver disease). In: Federici M, Menghini R (eds) Gut Microbiome, Microbial Metabolites and Cardiometabolic Risk. Springer.
Bhandari S, Kuehne S, Camilleri J. Assessment of a light-curable hydrogel to be used for root canal obturation. J Dent Res.
Hollingshead S, McVicker G, Nielsen MR, et al. Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system. mBio.
Shah SN, Knausenberger TB, Pontifex MG, et al. Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor. Gut Microbes.
Snobre J, Meehan CJ, Mulders W, et al. Frameshift mutations in the mmpR5 gene can have a bedaquiline-susceptible phenotype by retaining a protein structure and function similar to wild-type Mycobacterium tuberculosis. Antimicrob Agents Chemother.
Graf FE, Goodman RN, Gallichan S, et al. Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales. Nat Commun.
Read DS, Gweon HS, Bowes MJ, et al. Dissemination and persistence of antimicrobial resistance (AMR) along the wastewater-river continuum. Water Res.
Muchova M, Kuehne SA, Grant MM, et al. Fusobacterium nucleatum elicits subspecies-specific responses in human neutrophils. Front Cell Infect Microbiol.
Das, S.K., Negus, D. How do Gram-negative bacteria escape predation by Bdellovibrio bacteriovorus? npj Antimicrob Resist.
Chen JH, Raman V, Kuehne SA, Camilleri J, Hirschfeld J. Chemical, antibacterial, and cytotoxic properties of four different endodontic sealer leachates over time. J Endod.
Afolayan JS, Varney AM, Thomas JC, McLean S, Perry CC. A rapid microwave approach for 'one-pot' synthesis of antibiotic conjugated silver nanoparticles with antimicrobial activity against multi-drug resistant bacterial pathogens. Colloids Surf B Biointerfaces.
Shutt-McCabe J, Shaik K, Hoyles L, McVicker G. The plasmid-borne hipBA operon of Klebsiella michiganensis encodes a potent plasmid stabilization system. J Appl Microbiol.
Floras F, Mawere C, Singh M, et al. The putative virulence plasmid pYR4 of the fish pathogen Yersinia ruckeri Is conjugative and stabilized by a HigBA toxin–antitoxin system. Biology.
Varney AM, Smitten KL, Southam HM, et al. In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions. ACS Infect Dis.
Aly YM, Zhang Z, Ali N, et al. Ceramic conversion treated titanium implant abutments with gold for enhanced antimicrobial activity. Dent Mater.
McLean S. What is antimicrobial resistance and why is it a problem? In: Masey O'Neill H, Burton E, Scholey D Pre and Probiotics for Poultry Gut Health. CABI.
Muguruza AR, Odyniec ML, Manhota M, et al. Antibiotic entrapment in antibacterial micelles as a novel strategy for the delivery of challenging antibiotics from silica nanoparticles. Microporous and Mesoporous Materials.
Behruznia M, Marin M, Farhat M, Thomas JC, Domingo-Sananes MR, Meehan CJ. The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference. eLife.
Machado E, Vasconcellos S, Gomes L, et al. Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species. Microb Genom.
James B, Reesaul H, Kashif S, et al. The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli. NPJ Antimicrob Resist.
Varney AM, Mannix-Fisher E, Thomas JC, McLean S. Evaluation of phenotypic and genotypic methods for the identification and characterization of bacterial isolates recovered from catheter-associated urinary tract infections. J Appl Microbiol.
Tzfadia O, Gijsbers A, Vujkovic A, et al. Single nucleotide variation catalog from clinical isolates mapped on tertiary and quaternary structures of ESX-1-related proteins reveals critical regions as putative Mtb therapeutic targets. Microbiol Spectr.
Mekapothula S, Chrysanthou E, Hall J, Nekkalapudi PD, McLean S, Cave GWV. Antipathogenic applications of copper nanoparticles in air filtration systems. Materials (Basel).
Dahlquist-Axe G, Standeven FJ, Speller CF, Tedder A, Meehan CJ. Inferring diet, disease and antibiotic resistance from ancient human oral microbiomes. Microb Genom.
Bhandari SS, Palin W, Kuehne SA, Camilleri J. Investigating best practice for specimen preparation for biological testing of root canal sealers. Dent Mater.
Duodu R, Linke D, Leo JC. Fluorescent labeling of outer membrane proteins using the SpyCatcher-SpyTag system. Methods Mol Biol.
Meuskens I, Leo JC, Linke D. Recombinant expression and overproduction of transmembrane β-barrel proteins. Methods Mol Biol.
Aruhomukama D, Galiwango R, Meehan CJ, Asiimwe B. Enhancing genomics and bioinformatics access in Africa: an imperative leap. Lancet Microbe.
Domingo-Sananes MR, Meehan CJ. The population genetics of prokaryotic pangenomes. Nat Ecol Evol.
Beavan A, Domingo-Sananes MR, McInerney JO. Contingency, repeatability, and predictability in the evolution of a prokaryotic pangenome. Proc Natl Acad Sci U S A.
Hoyles L. Gut microbiome and hepatic steatosis (steatotic liver disease). In: Federici M, Menghini R (eds) Gut Microbiome, Microbial Metabolites and Cardiometabolic Risk. Springer.
2023
Karatas E, Hadis M, Palin WM, Milward MR, Kuehne SA, Camilleri J. Minimally invasive management of vital teeth requiring root canal therapy. Sci Rep.
Quesada-Vázquez S, Castells-Nobau A, Latorre J, et al. Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity. Cell Rep Med.
Musoke D, Lubega GB, Obeng MB, et al. Knowledge, perceptions and practices on antimicrobial resistance in humans and animals in Wakiso district, Uganda: a cross sectional study. PLOS Glob Public Health.
Meaza A, Riviere E, Bonsa Z, et al. Genomic transmission clusters and circulating lineages of Mycobacterium tuberculosis among refugees residing in refugee camps in Ethiopia. Infect Genet Evol.
Omorotionmwan BB, Wang H, Baker JP, et al. Chromosomal engineering of inducible isopropanol- butanol-ethanol production in Clostridium acetobutylicum. Front Bioeng Biotechnol.
Musoke D, Lubega GB, Gbadesire MS, et al. Antimicrobial stewardship in private pharmacies in Wakiso district, Uganda: a qualitative study. J Pharmaceut Policy Pract.
Matlock W, Lipworth S, Chau KK, et al. Enterobacterales plasmid sharing amongst human bloodstream infections, livestock, wastewater, and waterway niches in Oxfordshire, UK. Elife.
Garvey E, Rhead J, Suffian S, et al. High incidence of antibiotic resistance amongst isolates of Helicobacter pylori collected in Nottingham, UK, between 2001 and 2018. J Med Microbiol.
Negus D, Foster G, Hoyles L. Lelliottia amnigena recovered from the lung of a harbour porpoise, and comparative analyses with Lelliottia spp. Access Microbiol.
English J, Newberry F, Hoyles L, Patrick S, Stewart L. Genomic analyses of Bacteroides fragilis: subdivisions I and II represent distinct species. J Med Microbiol.
Eladawy M, Thomas JC, Hoyles L. Phenotypic and genomic characterization of Pseudomonas aeruginosa isolates recovered from catheter-associated urinary tract infections in an Egyptian hospital. Microb Genom.
Lempens P, Van Deun A, Aung KJM, et al. Borderline rpoB mutations transmit at the same rate as common rpoB mutations in a tuberculosis cohort in Bangladesh. Microb Genom.
Cuella-Martin I, Semuto Ngabonziza JC, Torrea G, et al. Rifampicin resistance conferring mutations among Mycobacterium tuberculosis strains in Rwanda. Int J Mycobacteriol.
Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, et al. Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide. Nat Commun.
Napier G, Couvin D, Refrégier G, et al. Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data. Sci Rep.
Walker AW, Hoyles L. Human microbiome myths and misconceptions. Nat Microbiol.
Wildsmith C, Thomas JC, Negus D. Complete genome sequence of Staphylococcus casei strain DSM 15096. Access Microbiol.
Molinaro A, Nemet I, Bel Lassen P, et al. Microbially produced imidazole propionate is associated with heart failure and mortality. JACC Heart Fail.
Ferreira AM, Vikulina A, Cave GWV, Loughlin M, Puddu D, Volodkin D. Vaterite-nanosilver hybrids with antibacterial properties and pH-triggered release. Materials Today Chemistry.
Ferreira AM, Vikulina A, Loughlin M, Volodkin D. How similar is the antibacterial activity of silver nanoparticles coated with different capping agents? RSC Adv.
Ferreira AM, Vikulina A, Cave GWV, Loughlin M, Puddu V, Volodkin D. Vaterite vectors for the protection, storage and release of silver nanoparticles. J Colloid Interface Sci.
Wilkinson D, Alsharaf L, Thompson S, et al. Characterization of a Helicobacter pylori strain with high biofilm-forming ability. J Med Microbiol.
McCartney AL, Hoyles L. The role of Klebsiella populations in preterm infants. Biochem Soc Trans.
Newberry F, Shibu P, Smith-Zaitlik T, et al. Lytic bacteriophage vB_KmiS-Kmi2C disrupts biofilms formed by members of the Klebsiella oxytoca complex, and represents a novel virus family and genus. J Appl Microbiol.
Alexander JA, Posma JM, Scott A, et al. Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer. Microbiome.
Lubega GB, Musoke D, Nakalawa S, Brandish C, et al. Scaling-up interventions for strengthening antimicrobial stewardship using a One Health approach in Wakiso District, Uganda. Med Sci Forum.
Randall DW, Kieswich J, Hoyles L, McCafferty K, Curtis M, Yaqoob M. Gut dysbiosis in experimental kidney disease: a meta-analysis of rodent repository data. J Am Soc Nephrol.
Quesada-Vázquez S, Castells-Nobau A, Latorre J, et al. Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity. Cell Rep Med.
Musoke D, Lubega GB, Obeng MB, et al. Knowledge, perceptions and practices on antimicrobial resistance in humans and animals in Wakiso district, Uganda: a cross sectional study. PLOS Glob Public Health.
Meaza A, Riviere E, Bonsa Z, et al. Genomic transmission clusters and circulating lineages of Mycobacterium tuberculosis among refugees residing in refugee camps in Ethiopia. Infect Genet Evol.
Omorotionmwan BB, Wang H, Baker JP, et al. Chromosomal engineering of inducible isopropanol- butanol-ethanol production in Clostridium acetobutylicum. Front Bioeng Biotechnol.
Musoke D, Lubega GB, Gbadesire MS, et al. Antimicrobial stewardship in private pharmacies in Wakiso district, Uganda: a qualitative study. J Pharmaceut Policy Pract.
Matlock W, Lipworth S, Chau KK, et al. Enterobacterales plasmid sharing amongst human bloodstream infections, livestock, wastewater, and waterway niches in Oxfordshire, UK. Elife.
Garvey E, Rhead J, Suffian S, et al. High incidence of antibiotic resistance amongst isolates of Helicobacter pylori collected in Nottingham, UK, between 2001 and 2018. J Med Microbiol.
Negus D, Foster G, Hoyles L. Lelliottia amnigena recovered from the lung of a harbour porpoise, and comparative analyses with Lelliottia spp. Access Microbiol.
English J, Newberry F, Hoyles L, Patrick S, Stewart L. Genomic analyses of Bacteroides fragilis: subdivisions I and II represent distinct species. J Med Microbiol.
Eladawy M, Thomas JC, Hoyles L. Phenotypic and genomic characterization of Pseudomonas aeruginosa isolates recovered from catheter-associated urinary tract infections in an Egyptian hospital. Microb Genom.
Lempens P, Van Deun A, Aung KJM, et al. Borderline rpoB mutations transmit at the same rate as common rpoB mutations in a tuberculosis cohort in Bangladesh. Microb Genom.
Cuella-Martin I, Semuto Ngabonziza JC, Torrea G, et al. Rifampicin resistance conferring mutations among Mycobacterium tuberculosis strains in Rwanda. Int J Mycobacteriol.
Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, et al. Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide. Nat Commun.
Napier G, Couvin D, Refrégier G, et al. Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data. Sci Rep.
Walker AW, Hoyles L. Human microbiome myths and misconceptions. Nat Microbiol.
Wildsmith C, Thomas JC, Negus D. Complete genome sequence of Staphylococcus casei strain DSM 15096. Access Microbiol.
Molinaro A, Nemet I, Bel Lassen P, et al. Microbially produced imidazole propionate is associated with heart failure and mortality. JACC Heart Fail.
Ferreira AM, Vikulina A, Cave GWV, Loughlin M, Puddu D, Volodkin D. Vaterite-nanosilver hybrids with antibacterial properties and pH-triggered release. Materials Today Chemistry.
Ferreira AM, Vikulina A, Loughlin M, Volodkin D. How similar is the antibacterial activity of silver nanoparticles coated with different capping agents? RSC Adv.
Ferreira AM, Vikulina A, Cave GWV, Loughlin M, Puddu V, Volodkin D. Vaterite vectors for the protection, storage and release of silver nanoparticles. J Colloid Interface Sci.
Wilkinson D, Alsharaf L, Thompson S, et al. Characterization of a Helicobacter pylori strain with high biofilm-forming ability. J Med Microbiol.
McCartney AL, Hoyles L. The role of Klebsiella populations in preterm infants. Biochem Soc Trans.
Newberry F, Shibu P, Smith-Zaitlik T, et al. Lytic bacteriophage vB_KmiS-Kmi2C disrupts biofilms formed by members of the Klebsiella oxytoca complex, and represents a novel virus family and genus. J Appl Microbiol.
Alexander JA, Posma JM, Scott A, et al. Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer. Microbiome.
Lubega GB, Musoke D, Nakalawa S, Brandish C, et al. Scaling-up interventions for strengthening antimicrobial stewardship using a One Health approach in Wakiso District, Uganda. Med Sci Forum.
Randall DW, Kieswich J, Hoyles L, McCafferty K, Curtis M, Yaqoob M. Gut dysbiosis in experimental kidney disease: a meta-analysis of rodent repository data. J Am Soc Nephrol.
2022
Wilkinson DJ, Dickins B, Robinson K, Winter JA. Genomic diversity of Helicobacter pylori populations from different regions of the human stomach. Gut Microbes.
Rimmer CO, Thomas JC. Complete genome sequence of Staphylococcus edaphicus strain CCM 8731. Microbiol Resour Announc.
Penney N, Yeung D, Garcia-Perez I, et al. Multi-omic phenotyping reveals host-microbe responses to bariatric surgery, glycaemic control and obesity. Commun Med.
Smith-Zaitlik T, Shibu P, McCartney AL, Foster G, Hoyles L, Negus D. Extended genomic analyses of the broad-host-range phages vB_KmiM-2Di and vB_KmiM-4Dii reveal slopekviruses have highly conserved genomes. Microbiology.
Van Rie A, Walker T, de Jong B, et al. Balancing access to BPaLM regimens and risk of resistance. Lancet.
Stachulski AV, Knausenberger TBA, Shah SN, Hoyles L, McArthur S. A host–gut microbial co-metabolite of aromatic amino acids, p-cresol glucuronide, promotes blood–brain barrier integrity in vivo. Tissue Barriers.
Chandaluri S, Thomas JC. Whole-genome sequence of Psychromonas antarctica strain DSM 10704. Microbiol Resour Announc.
Oostvogels S, Ley SD, Heupink TH, et al. Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa. Microb Genom.
Ngabonziza JCS, Rigouts L, Torrea G, et al. Multidrug-resistant tuberculosis control in Rwanda overcomes a successful clone that causes most disease over a quarter century. J Clin Tuberc Other Mycobact Dis.
Edwards T, Heinz E, van Aartsen J, et al. Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types. Microb Genom.
Noble A, Pring ET, Durant L, et al. Altered immunity to microbiota, B cell activation and depleted γδ/resident memory T cells in colorectal cancer. Cancer Immunol Immunother.
Noble A, Durant L, Dilke SM, et al. Altered mucosal immune-microbiota interactions in familial adenomatous polyposis. Clin Transl Gastroenterol.
Manyahi J, Moyo SJ, Kibwana U, et al. First identification of blaNDM-5 producing Escherichia coli from neonates and a HIV infected adult in Tanzania. J Med Microbiol.
Fromentin S, Forslund SK, Chechi K, et al. Microbiome and metabolome features of the cardiometabolic disease spectrum. Nat Med.
Menghini R, Hoyles L, Cardellini M, et al. ITCH E3 Ubiquitin Ligase downregulation compromises hepatic degradation of branched-chain amino acids. Mol Metab.
Rayment S, Garrie K, Kaur I, et al. Investigating student engagement and making science real during a pandemic: Bioskills at Home, a case study. Edu Sci.
Chakrabarti A, Geurts L, Hoyles L, et al. The microbiota-gut-brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice. Cell Mol Life Sci.
Hermansen S, Linke D, Leo JC. Transmembrane β-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Belda E, Voland L, Tremaroli V, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut.
Michalik M, Djahanschiri B, Leo JC, Linke D. An update on "reverse vaccinology": the pathway from genomes and epitope predictions to tailored, recombinant vaccines. Methods Mol Biol.
Rimmer CO, Thomas JC. Complete genome sequence of Staphylococcus edaphicus strain CCM 8731. Microbiol Resour Announc.
Penney N, Yeung D, Garcia-Perez I, et al. Multi-omic phenotyping reveals host-microbe responses to bariatric surgery, glycaemic control and obesity. Commun Med.
Smith-Zaitlik T, Shibu P, McCartney AL, Foster G, Hoyles L, Negus D. Extended genomic analyses of the broad-host-range phages vB_KmiM-2Di and vB_KmiM-4Dii reveal slopekviruses have highly conserved genomes. Microbiology.
Van Rie A, Walker T, de Jong B, et al. Balancing access to BPaLM regimens and risk of resistance. Lancet.
Stachulski AV, Knausenberger TBA, Shah SN, Hoyles L, McArthur S. A host–gut microbial co-metabolite of aromatic amino acids, p-cresol glucuronide, promotes blood–brain barrier integrity in vivo. Tissue Barriers.
Chandaluri S, Thomas JC. Whole-genome sequence of Psychromonas antarctica strain DSM 10704. Microbiol Resour Announc.
Oostvogels S, Ley SD, Heupink TH, et al. Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa. Microb Genom.
Ngabonziza JCS, Rigouts L, Torrea G, et al. Multidrug-resistant tuberculosis control in Rwanda overcomes a successful clone that causes most disease over a quarter century. J Clin Tuberc Other Mycobact Dis.
Edwards T, Heinz E, van Aartsen J, et al. Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types. Microb Genom.
Noble A, Pring ET, Durant L, et al. Altered immunity to microbiota, B cell activation and depleted γδ/resident memory T cells in colorectal cancer. Cancer Immunol Immunother.
Noble A, Durant L, Dilke SM, et al. Altered mucosal immune-microbiota interactions in familial adenomatous polyposis. Clin Transl Gastroenterol.
Manyahi J, Moyo SJ, Kibwana U, et al. First identification of blaNDM-5 producing Escherichia coli from neonates and a HIV infected adult in Tanzania. J Med Microbiol.
Fromentin S, Forslund SK, Chechi K, et al. Microbiome and metabolome features of the cardiometabolic disease spectrum. Nat Med.
Menghini R, Hoyles L, Cardellini M, et al. ITCH E3 Ubiquitin Ligase downregulation compromises hepatic degradation of branched-chain amino acids. Mol Metab.
Rayment S, Garrie K, Kaur I, et al. Investigating student engagement and making science real during a pandemic: Bioskills at Home, a case study. Edu Sci.
Chakrabarti A, Geurts L, Hoyles L, et al. The microbiota-gut-brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice. Cell Mol Life Sci.
Hermansen S, Linke D, Leo JC. Transmembrane β-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Belda E, Voland L, Tremaroli V, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut.
Michalik M, Djahanschiri B, Leo JC, Linke D. An update on "reverse vaccinology": the pathway from genomes and epitope predictions to tailored, recombinant vaccines. Methods Mol Biol.
2021
Forslund SK, Chakaroun R, Zimmermann-Kogadeeva M, et al. Combinatorial, additive and dose-dependent drug–microbiome associations. Nature.
Hoyles L, Pontifex MG, Rodriguez-Romiro I, et al. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome.
Roberfroid M, Gibson GR, Hoyles L, et al. Commentary on : Prebiotic effects: metabolic and health benefits. Br J Nutr.
Nalpas N, Hoyles L, Anselm V, et al. An integrated workflow for enhanced taxonomic and functional coverage of the mouse faecal metaproteome. Gut Microbes.
Hsieh SY, Tariq MA, Telatin A, et al. Comparison of PCR versus PCR-free DNA library preparation for characterizing the human faecal virome. Viruses.
Vrijheid M, Basagaña X, Gonzalez JR, et al. Advancing tools for human early lifecourse exposome research and translation (ATHLETE): project overview. Environ Epidemiol.
Musoke D, Namata C, Lubega GB, et al. Access, use and disposal of antimicrobials among humans and animals in Wakiso district, Uganda: a qualitative study. Pharm Policy Pract.
Hermansen S, Linke D, Leo JC. Transmembrane beta-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Blundell-Hunter G, Enright MC, Negus D, et al. Characterisation of bacteriophage-encoded depolymerases selective for key Klebsiella pneumoniae capsular exopolysaccharides. Front Cell Infect Microbiol.
Shibu P, McCuaig F, McCartney AL, Kujawska M, Hall LJ, Hoyles, L. Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster. Microb Genom.
Brial F, Chilloux J, Nielsen T et al. Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health. Gut.
Mayneris-Perxachs J, Cardellini M, Hoyles L, et al. Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome. Microbiome.
Mannix-Fisher E, McLean S. The antimicrobial activity of silver acetate against Acinetobacter baumannii in a Galleria mellonella infection model. PeerJ.
Rooke JL, Icke C, Wells TJ, et al. BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Front Microbiol.
Domingo-Sananes MR, McInerney JO. Mechanisms that shape microbial pangenomes. Trends Microbiol.
Hill HN, Wilkinson DJ, Le Bon M. Oregano essential oil improves piglet health and performance through maternal feeding and is associated with changes in the gut microbiota. Animal Microbiome.
Hoyles L, Pontifex MG, Rodriguez-Romiro I, et al. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome.
Roberfroid M, Gibson GR, Hoyles L, et al. Commentary on : Prebiotic effects: metabolic and health benefits. Br J Nutr.
Nalpas N, Hoyles L, Anselm V, et al. An integrated workflow for enhanced taxonomic and functional coverage of the mouse faecal metaproteome. Gut Microbes.
Hsieh SY, Tariq MA, Telatin A, et al. Comparison of PCR versus PCR-free DNA library preparation for characterizing the human faecal virome. Viruses.
Vrijheid M, Basagaña X, Gonzalez JR, et al. Advancing tools for human early lifecourse exposome research and translation (ATHLETE): project overview. Environ Epidemiol.
Musoke D, Namata C, Lubega GB, et al. Access, use and disposal of antimicrobials among humans and animals in Wakiso district, Uganda: a qualitative study. Pharm Policy Pract.
Hermansen S, Linke D, Leo JC. Transmembrane beta-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Blundell-Hunter G, Enright MC, Negus D, et al. Characterisation of bacteriophage-encoded depolymerases selective for key Klebsiella pneumoniae capsular exopolysaccharides. Front Cell Infect Microbiol.
Shibu P, McCuaig F, McCartney AL, Kujawska M, Hall LJ, Hoyles, L. Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster. Microb Genom.
Brial F, Chilloux J, Nielsen T et al. Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health. Gut.
Mayneris-Perxachs J, Cardellini M, Hoyles L, et al. Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome. Microbiome.
Mannix-Fisher E, McLean S. The antimicrobial activity of silver acetate against Acinetobacter baumannii in a Galleria mellonella infection model. PeerJ.
Rooke JL, Icke C, Wells TJ, et al. BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Front Microbiol.
Domingo-Sananes MR, McInerney JO. Mechanisms that shape microbial pangenomes. Trends Microbiol.
Hill HN, Wilkinson DJ, Le Bon M. Oregano essential oil improves piglet health and performance through maternal feeding and is associated with changes in the gut microbiota. Animal Microbiome.
2020
Varney AM, Smitten KL, Thomas JA, et al. Transcriptomic analysis of the activity and mechanism of action of a ruthenium(II)-based antimicrobial that induces minimal evolution of pathogen resistance. ACS Pharmacol Trans Sci.
Weikum J, Kulakova A, Tesei G, et al. The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Sci Rep.
Musoke D, Kitutu FE, Mugisha L, et al. A one health approach to strengthening antimicrobial stewardship in Wakiso District, Uganda. Antibiotics.
Tariq MA, Newberry F, Haagmans R, et al. Genome characterization of a novel wastewater Bacteroides fragilis bacteriophage (vB_BfrS_23) and its host GB124. Front Microbiol.
D’Amato A, Di Cesare Mannelli L, Lucarini E, et al. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome.
Khalil HS, Øgaard J, Leo JC. Coaggregation properties of trimeric autotransporter adhesins. MicrobiologyOpen.
Kujawska M, La Rosa SL, Roger LC, et al. Succession of Bifidobacterium longum strains in response to a changing early life nutritional environment reveals dietary substrate adaptations. iScience.
Whelan R, McVicker G, Leo JC. Staying out or going in? The interplay between type 3 and type 5 secretion systems in adhesion and invasion of enterobacterial pathogens. Int J Mol Sci.
Wrobel A, Saragliadis A, Perez-Ortega J, et al. The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. Environ Microbiol.
Murray BO, Dawson RA, Alsharaf LM, Winter JA. Protective effects of Helicobacter pylori membrane vesicles against stress and antimicrobial agents. Microbiology.
Noble A, Durant L, Hoyles L, et al. Deficient resident memory T cell and CD8 T cell response to commensals in inflammatory bowel disease. J Crohns Colitis.
Durant L, Stentz R, Noble A, et al. Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome.
Leterte MPM, Munjoma N, Wolfer K, et al. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. J Proteome Res.
Mayneris-Perxachs J, Puig J, Burcelin R, et al. The APOA1bp-SREBF-NOTCH axis is associated with reduced atherosclerosis risk in morbidly obese patients. Clin Nutr.
Leggett RM, Alcon-Giner C, Heavens D, et al. Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathgens. Nat Microbiol.
Herridge WP, Shibu P, O'Shea J, et al. Bacteriophages of Klebsiella spp., their diversity and potential therapeutic uses. J Med Microbiol.
Chen Y, Brook TC, Soe CZ, et al. Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors. Microb Genom.
Weikum J, Kulakova A, Tesei G, et al. The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Sci Rep.
Musoke D, Kitutu FE, Mugisha L, et al. A one health approach to strengthening antimicrobial stewardship in Wakiso District, Uganda. Antibiotics.
Tariq MA, Newberry F, Haagmans R, et al. Genome characterization of a novel wastewater Bacteroides fragilis bacteriophage (vB_BfrS_23) and its host GB124. Front Microbiol.
D’Amato A, Di Cesare Mannelli L, Lucarini E, et al. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome.
Khalil HS, Øgaard J, Leo JC. Coaggregation properties of trimeric autotransporter adhesins. MicrobiologyOpen.
Kujawska M, La Rosa SL, Roger LC, et al. Succession of Bifidobacterium longum strains in response to a changing early life nutritional environment reveals dietary substrate adaptations. iScience.
Whelan R, McVicker G, Leo JC. Staying out or going in? The interplay between type 3 and type 5 secretion systems in adhesion and invasion of enterobacterial pathogens. Int J Mol Sci.
Wrobel A, Saragliadis A, Perez-Ortega J, et al. The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. Environ Microbiol.
Murray BO, Dawson RA, Alsharaf LM, Winter JA. Protective effects of Helicobacter pylori membrane vesicles against stress and antimicrobial agents. Microbiology.
Noble A, Durant L, Hoyles L, et al. Deficient resident memory T cell and CD8 T cell response to commensals in inflammatory bowel disease. J Crohns Colitis.
Durant L, Stentz R, Noble A, et al. Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome.
Leterte MPM, Munjoma N, Wolfer K, et al. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. J Proteome Res.
Mayneris-Perxachs J, Puig J, Burcelin R, et al. The APOA1bp-SREBF-NOTCH axis is associated with reduced atherosclerosis risk in morbidly obese patients. Clin Nutr.
Leggett RM, Alcon-Giner C, Heavens D, et al. Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathgens. Nat Microbiol.
Herridge WP, Shibu P, O'Shea J, et al. Bacteriophages of Klebsiella spp., their diversity and potential therapeutic uses. J Med Microbiol.
Chen Y, Brook TC, Soe CZ, et al. Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors. Microb Genom.
2019
ElTahir Y, Al-Araimi A, Nair RR, et al. Binding of Brucella protein, Bp26, to select extracellular matrix molecules. BMC Mol Cell Biol.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequences of Citrobacter freundii and Citrobacter murliniae strains isolated from the feces of preterm infants. Microbiol Resour Announc.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of a preterm infant. Microbiol Resour Announc.
Dao MC, Sokolovska N, Brazeilles R, et al. A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity. Front Physiol.
Davies C, Taylor AJ, Elmi A, et al. Sodium taurocholate stimulates Campylobacter jejuni outer membrane vesicle production via down-regulation of the maintenance of lipid asymmetry pathway. Front Cell Infect Microbiol.
McVicker G. Overcoming addiction in bacteria: how to disable a deadly E. coli outbreak. MiSAC.
McVicker G, Hollingshead S, Pilla G, Tang CM. Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems. Mol Microbiol.
Hoyles L. Spotlight on… Lesley Hoyles. FEMS Microbiol Lett.
Raghunathan D, Radford PM, Gell C, et al. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential. Sci Rep.
Randall DW, Kieswich J, Swann J, et al. Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale. Microbiome.
Trunk T, Casasanta MA, Yoo CC, Slade DJ, Leo JC. Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle. Biochem J.
Wrobel A, Leo JC, Linke D. Overcoming fish defences: the virulence factors of Yersinia ruckeri. Genes (Basel).
Hoyles L, Wallace RJ. Gastrointestinal tract: fat metabolism in the colon. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Wallace RJ. Gastrointestinal tract: intestinal fatty acid metabolism and implications for health. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Swann J. Influence of the human gut microbiome on the metabolic phenotype. In: Lindon JC, Nicholson JK, Holmes E (eds) The Handbook of Metabolic Phenotyping. Elsevier.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequences of Citrobacter freundii and Citrobacter murliniae strains isolated from the feces of preterm infants. Microbiol Resour Announc.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of a preterm infant. Microbiol Resour Announc.
Dao MC, Sokolovska N, Brazeilles R, et al. A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity. Front Physiol.
Davies C, Taylor AJ, Elmi A, et al. Sodium taurocholate stimulates Campylobacter jejuni outer membrane vesicle production via down-regulation of the maintenance of lipid asymmetry pathway. Front Cell Infect Microbiol.
McVicker G. Overcoming addiction in bacteria: how to disable a deadly E. coli outbreak. MiSAC.
McVicker G, Hollingshead S, Pilla G, Tang CM. Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems. Mol Microbiol.
Hoyles L. Spotlight on… Lesley Hoyles. FEMS Microbiol Lett.
Raghunathan D, Radford PM, Gell C, et al. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential. Sci Rep.
Randall DW, Kieswich J, Swann J, et al. Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale. Microbiome.
Trunk T, Casasanta MA, Yoo CC, Slade DJ, Leo JC. Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle. Biochem J.
Wrobel A, Leo JC, Linke D. Overcoming fish defences: the virulence factors of Yersinia ruckeri. Genes (Basel).
Hoyles L, Wallace RJ. Gastrointestinal tract: fat metabolism in the colon. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Wallace RJ. Gastrointestinal tract: intestinal fatty acid metabolism and implications for health. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Swann J. Influence of the human gut microbiome on the metabolic phenotype. In: Lindon JC, Nicholson JK, Holmes E (eds) The Handbook of Metabolic Phenotyping. Elsevier.
2018
Dickins TE, Dickins BJA. The extent of the modern synthesis: the foundational framework for evolutionary biology. In: Burggren W, Dubansky B (eds) Development and Environment. Springer.
Wareham LK, McLean S, Begg R, et al. The broad-spectrum antimicrobial potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a water-soluble CO-releasing molecule (CORM-401): intracellular accumulation, transcriptomic and statistical analyses, and membrane polarization. Antioxid Redox Signal.
Hoyles L, Fernández-Real JM, Federici M, et al. Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women. Nat Med.
Hoyles L, Jiménez-Pranteda ML, Chilloux J, et al. Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome.
Hoyles L, Snelling T, Umlai UK, et al. Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Microbiome.
McVicker G, Prajsnar TK, Foster SJ. Construction and use of Staphylococcus aureus strains to study within-host infection dynamics. Methods Mol Biol.
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of larval zebrafish model to study within-host infection dynamics. Methods Mol Biol.
Wareham LK, McLean S, Begg R, et al. The broad-spectrum antimicrobial potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a water-soluble CO-releasing molecule (CORM-401): intracellular accumulation, transcriptomic and statistical analyses, and membrane polarization. Antioxid Redox Signal.
Hoyles L, Fernández-Real JM, Federici M, et al. Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women. Nat Med.
Hoyles L, Jiménez-Pranteda ML, Chilloux J, et al. Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome.
Hoyles L, Snelling T, Umlai UK, et al. Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Microbiome.
McVicker G, Prajsnar TK, Foster SJ. Construction and use of Staphylococcus aureus strains to study within-host infection dynamics. Methods Mol Biol.
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of larval zebrafish model to study within-host infection dynamics. Methods Mol Biol.
