2022
Chakrabarti A, Geurts L, Hoyles L, et al. The microbiota-gut-brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice. Cell Mol Life Sci.
Hermansen S, Linke D, Leo JC. Transmembrane β-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Belda E, Voland L, Tremaroli V, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut.
Michalik M, Djahanschiri B, Leo JC, Linke D. An update on "reverse vaccinology": the pathway from genomes and epitope predictions to tailored, recombinant vaccines. Methods Mol Biol.
Hermansen S, Linke D, Leo JC. Transmembrane β-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Belda E, Voland L, Tremaroli V, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut.
Michalik M, Djahanschiri B, Leo JC, Linke D. An update on "reverse vaccinology": the pathway from genomes and epitope predictions to tailored, recombinant vaccines. Methods Mol Biol.
2021
Forslund SK, Chakaroun R, Zimmermann-Kogadeeva M, et al. Combinatorial, additive and dose-dependent drug–microbiome associations. Nature.
Hoyles L, Pontifex MG, Rodriguez-Romiro I, et al. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome.
Roberfroid M, Gibson GR, Hoyles L, et al. Commentary on : Prebiotic effects: metabolic and health benefits. Br J Nutr.
Nalpas N, Hoyles L, Anselm V, et al. An integrated workflow for enhanced taxonomic and functional coverage of the mouse faecal metaproteome. Gut Microbes.
Hsieh SY, Tariq MA, Telatin A, et al. Comparison of PCR versus PCR-free DNA library preparation for characterizing the human faecal virome. Viruses.
Vrijheid M, Basagaña X, Gonzalez JR, et al. Advancing tools for human early lifecourse exposome research and translation (ATHLETE): project overview. Environ Epidemiol.
Musoke D, Namata C, Lubega GB, et al. Access, use and disposal of antimicrobials among humans and animals in Wakiso district, Uganda: a qualitative study. Pharm Policy Pract.
Hermansen S, Linke D, Leo JC. Transmembrane beta-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Blundell-Hunter G, Enright MC, Negus D, et al. Characterisation of bacteriophage-encoded depolymerases selective for key Klebsiella pneumoniae capsular exopolysaccharides. Front Cell Infect Microbiol.
Shibu P, McCuaig F, McCartney AL, Kujawska M, Hall LJ, Hoyles, L. Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster. Microb Genom.
Brial F, Chilloux J, Nielsen T et al. Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health. Gut.
Mayneris-Perxachs J, Cardellini M, Hoyles L, et al. Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome. Microbiome.
Mannix-Fisher E, McLean S. The antimicrobial activity of silver acetate against Acinetobacter baumannii in a Galleria mellonella infection model. PeerJ.
Rooke JL, Icke C, Wells TJ, et al. BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Front Microbiol.
Domingo-Sananes MR, McInerney JO. Mechanisms that shape microbial pangenomes. Trends Microbiol.
Hill HN, Wilkinson DJ, Le Bon M. Oregano essential oil improves piglet health and performance through maternal feeding and is associated with changes in the gut microbiota. Animal Microbiome.
Hoyles L, Pontifex MG, Rodriguez-Romiro I, et al. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. Microbiome.
Roberfroid M, Gibson GR, Hoyles L, et al. Commentary on : Prebiotic effects: metabolic and health benefits. Br J Nutr.
Nalpas N, Hoyles L, Anselm V, et al. An integrated workflow for enhanced taxonomic and functional coverage of the mouse faecal metaproteome. Gut Microbes.
Hsieh SY, Tariq MA, Telatin A, et al. Comparison of PCR versus PCR-free DNA library preparation for characterizing the human faecal virome. Viruses.
Vrijheid M, Basagaña X, Gonzalez JR, et al. Advancing tools for human early lifecourse exposome research and translation (ATHLETE): project overview. Environ Epidemiol.
Musoke D, Namata C, Lubega GB, et al. Access, use and disposal of antimicrobials among humans and animals in Wakiso district, Uganda: a qualitative study. Pharm Policy Pract.
Hermansen S, Linke D, Leo JC. Transmembrane beta-barrel proteins of bacteria: from structure to function. Adv Protein Chem Struct Biol.
Blundell-Hunter G, Enright MC, Negus D, et al. Characterisation of bacteriophage-encoded depolymerases selective for key Klebsiella pneumoniae capsular exopolysaccharides. Front Cell Infect Microbiol.
Shibu P, McCuaig F, McCartney AL, Kujawska M, Hall LJ, Hoyles, L. Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster. Microb Genom.
Brial F, Chilloux J, Nielsen T et al. Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health. Gut.
Mayneris-Perxachs J, Cardellini M, Hoyles L, et al. Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome. Microbiome.
Mannix-Fisher E, McLean S. The antimicrobial activity of silver acetate against Acinetobacter baumannii in a Galleria mellonella infection model. PeerJ.
Rooke JL, Icke C, Wells TJ, et al. BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Front Microbiol.
Domingo-Sananes MR, McInerney JO. Mechanisms that shape microbial pangenomes. Trends Microbiol.
Hill HN, Wilkinson DJ, Le Bon M. Oregano essential oil improves piglet health and performance through maternal feeding and is associated with changes in the gut microbiota. Animal Microbiome.
2020
Varney AM, Smitten KL, Thomas JA, et al. Transcriptomic analysis of the activity and mechanism of action of a ruthenium(II)-based antimicrobial that induces minimal evolution of pathogen resistance. ACS Pharmacol Trans Sci.
Weikum J, Kulakova A, Tesei G, et al. The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Sci Rep.
Musoke D, Kitutu FE, Mugisha L, et al. A one health approach to strengthening antimicrobial stewardship in Wakiso District, Uganda. Antibiotics.
Tariq MA, Newberry F, Haagmans R, et al. Genome characterization of a novel wastewater Bacteroides fragilis bacteriophage (vB_BfrS_23) and its host GB124. Front Microbiol.
D’Amato A, Di Cesare Mannelli L, Lucarini E, et al. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome.
Khalil HS, Øgaard J, Leo JC. Coaggregation properties of trimeric autotransporter adhesins. MicrobiologyOpen.
Kujawska M, La Rosa SL, Roger LC, et al. Succession of Bifidobacterium longum strains in response to a changing early life nutritional environment reveals dietary substrate adaptations. iScience.
Whelan R, McVicker G, Leo JC. Staying out or going in? The interplay between type 3 and type 5 secretion systems in adhesion and invasion of enterobacterial pathogens. Int J Mol Sci.
Wrobel A, Saragliadis A, Perez-Ortega J, et al. The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. Environ Microbiol.
Murray BO, Dawson RA, Alsharaf LM, Winter JA. Protective effects of Helicobacter pylori membrane vesicles against stress and antimicrobial agents. Microbiology.
Noble A, Durant L, Hoyles L, et al. Deficient resident memory T cell and CD8 T cell response to commensals in inflammatory bowel disease. J Crohns Colitis.
Durant L, Stentz R, Noble A, et al. Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome.
Leterte MPM, Munjoma N, Wolfer K, et al. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. J Proteome Res.
Mayneris-Perxachs J, Puig J, Burcelin R, et al. The APOA1bp-SREBF-NOTCH axis is associated with reduced atherosclerosis risk in morbidly obese patients. Clin Nutr.
Leggett RM, Alcon-Giner C, Heavens D, et al. Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathgens. Nat Microbiol.
Herridge WP, Shibu P, O'Shea J, et al. Bacteriophages of Klebsiella spp., their diversity and potential therapeutic uses. J Med Microbiol.
Chen Y, Brook TC, Soe CZ, et al. Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors. Microb Genom.
Weikum J, Kulakova A, Tesei G, et al. The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Sci Rep.
Musoke D, Kitutu FE, Mugisha L, et al. A one health approach to strengthening antimicrobial stewardship in Wakiso District, Uganda. Antibiotics.
Tariq MA, Newberry F, Haagmans R, et al. Genome characterization of a novel wastewater Bacteroides fragilis bacteriophage (vB_BfrS_23) and its host GB124. Front Microbiol.
D’Amato A, Di Cesare Mannelli L, Lucarini E, et al. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome.
Khalil HS, Øgaard J, Leo JC. Coaggregation properties of trimeric autotransporter adhesins. MicrobiologyOpen.
Kujawska M, La Rosa SL, Roger LC, et al. Succession of Bifidobacterium longum strains in response to a changing early life nutritional environment reveals dietary substrate adaptations. iScience.
Whelan R, McVicker G, Leo JC. Staying out or going in? The interplay between type 3 and type 5 secretion systems in adhesion and invasion of enterobacterial pathogens. Int J Mol Sci.
Wrobel A, Saragliadis A, Perez-Ortega J, et al. The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. Environ Microbiol.
Murray BO, Dawson RA, Alsharaf LM, Winter JA. Protective effects of Helicobacter pylori membrane vesicles against stress and antimicrobial agents. Microbiology.
Noble A, Durant L, Hoyles L, et al. Deficient resident memory T cell and CD8 T cell response to commensals in inflammatory bowel disease. J Crohns Colitis.
Durant L, Stentz R, Noble A, et al. Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome.
Leterte MPM, Munjoma N, Wolfer K, et al. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. J Proteome Res.
Mayneris-Perxachs J, Puig J, Burcelin R, et al. The APOA1bp-SREBF-NOTCH axis is associated with reduced atherosclerosis risk in morbidly obese patients. Clin Nutr.
Leggett RM, Alcon-Giner C, Heavens D, et al. Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathgens. Nat Microbiol.
Herridge WP, Shibu P, O'Shea J, et al. Bacteriophages of Klebsiella spp., their diversity and potential therapeutic uses. J Med Microbiol.
Chen Y, Brook TC, Soe CZ, et al. Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors. Microb Genom.
2019
ElTahir Y, Al-Araimi A, Nair RR, et al. Binding of Brucella protein, Bp26, to select extracellular matrix molecules. BMC Mol Cell Biol.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequences of Citrobacter freundii and Citrobacter murliniae strains isolated from the feces of preterm infants. Microbiol Resour Announc.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of a preterm infant. Microbiol Resour Announc.
Dao MC, Sokolovska N, Brazeilles R, et al. A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity. Front Physiol.
Davies C, Taylor AJ, Elmi A, et al. Sodium taurocholate stimulates Campylobacter jejuni outer membrane vesicle production via down-regulation of the maintenance of lipid asymmetry pathway. Front Cell Infect Microbiol.
McVicker G. Overcoming addiction in bacteria: how to disable a deadly E. coli outbreak. MiSAC.
McVicker G, Hollingshead S, Pilla G, Tang CM. Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems. Mol Microbiol.
Hoyles L. Spotlight on… Lesley Hoyles. FEMS Microbiol Lett.
Raghunathan D, Radford PM, Gell C, et al. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential. Sci Rep.
Randall DW, Kieswich J, Swann J, et al. Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale. Microbiome.
Trunk T, Casasanta MA, Yoo CC, Slade DJ, Leo JC. Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle. Biochem J.
Wrobel A, Leo JC, Linke D. Overcoming fish defences: the virulence factors of Yersinia ruckeri. Genes (Basel).
Hoyles L, Wallace RJ. Gastrointestinal tract: fat metabolism in the colon. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Wallace RJ. Gastrointestinal tract: intestinal fatty acid metabolism and implications for health. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Swann J. Influence of the human gut microbiome on the metabolic phenotype. In: Lindon JC, Nicholson JK, Holmes E (eds) The Handbook of Metabolic Phenotyping. Elsevier.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequences of Citrobacter freundii and Citrobacter murliniae strains isolated from the feces of preterm infants. Microbiol Resour Announc.
Chen Y, Brook TC, Alcon-Giner C, Clarke P, Hall LJ, Hoyles L. Draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of a preterm infant. Microbiol Resour Announc.
Dao MC, Sokolovska N, Brazeilles R, et al. A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity. Front Physiol.
Davies C, Taylor AJ, Elmi A, et al. Sodium taurocholate stimulates Campylobacter jejuni outer membrane vesicle production via down-regulation of the maintenance of lipid asymmetry pathway. Front Cell Infect Microbiol.
McVicker G. Overcoming addiction in bacteria: how to disable a deadly E. coli outbreak. MiSAC.
McVicker G, Hollingshead S, Pilla G, Tang CM. Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems. Mol Microbiol.
Hoyles L. Spotlight on… Lesley Hoyles. FEMS Microbiol Lett.
Raghunathan D, Radford PM, Gell C, et al. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential. Sci Rep.
Randall DW, Kieswich J, Swann J, et al. Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale. Microbiome.
Trunk T, Casasanta MA, Yoo CC, Slade DJ, Leo JC. Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle. Biochem J.
Wrobel A, Leo JC, Linke D. Overcoming fish defences: the virulence factors of Yersinia ruckeri. Genes (Basel).
Hoyles L, Wallace RJ. Gastrointestinal tract: fat metabolism in the colon. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Wallace RJ. Gastrointestinal tract: intestinal fatty acid metabolism and implications for health. In: Goldfine H (ed.) Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer.
Hoyles L, Swann J. Influence of the human gut microbiome on the metabolic phenotype. In: Lindon JC, Nicholson JK, Holmes E (eds) The Handbook of Metabolic Phenotyping. Elsevier.
2018
Dickins TE, Dickins BJA. The extent of the modern synthesis: the foundational framework for evolutionary biology. In: Burggren W, Dubansky B (eds) Development and Environment. Springer.
Wareham LK, McLean S, Begg R, et al. The broad-spectrum antimicrobial potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a water-soluble CO-releasing molecule (CORM-401): intracellular accumulation, transcriptomic and statistical analyses, and membrane polarization. Antioxid Redox Signal.
Hoyles L, Fernández-Real JM, Federici M, et al. Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women. Nat Med.
Hoyles L, Jiménez-Pranteda ML, Chilloux J, et al. Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome.
Hoyles L, Snelling T, Umlai UK, et al. Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Microbiome.
McVicker G, Prajsnar TK, Foster SJ. Construction and use of Staphylococcus aureus strains to study within-host infection dynamics. Methods Mol Biol.
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of larval zebrafish model to study within-host infection dynamics. Methods Mol Biol.
Wareham LK, McLean S, Begg R, et al. The broad-spectrum antimicrobial potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a water-soluble CO-releasing molecule (CORM-401): intracellular accumulation, transcriptomic and statistical analyses, and membrane polarization. Antioxid Redox Signal.
Hoyles L, Fernández-Real JM, Federici M, et al. Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women. Nat Med.
Hoyles L, Jiménez-Pranteda ML, Chilloux J, et al. Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome.
Hoyles L, Snelling T, Umlai UK, et al. Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. Microbiome.
McVicker G, Prajsnar TK, Foster SJ. Construction and use of Staphylococcus aureus strains to study within-host infection dynamics. Methods Mol Biol.
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of larval zebrafish model to study within-host infection dynamics. Methods Mol Biol.
